Estimate your costs accurately. One of the most common mistakes for all entrepreneurs is underestimating costs. You must calculate not only the costs of doing business, such as wages and cleaning supplies, but also the overhead expenses such as insurance, bonding, vehicle maintenance, marketing and marketing materials, cell phones and so on. You should also plan for late payments or occasional non-payments from some of your customers, and the cost of collections.

Price your services appropriately. Businesses are often accustomed to paying more for the same service than residential customers would pay, so you may be able to charge more. Structure your pricing models to be favorable to your specific types of customers. If most of the businesses you serve are in a cyclical industry, you may work with them to clean offices more often during heavy traffic times of year and less often during down times, while charging a flat annual fee. One of the biggest advantages you have as a business to business service provider is the ability to lock in contracts and thus guarantee yourself a steady supply of work. Price your services to encourage contracts.

Screen your employees thoroughly. Whether you employ them directly or contract them at an hourly rate, your employees are the face of your business. Ensure that they are always dressed professionally, perhaps even in uniform. If you will not be on site during all cleaning engagements, ensure that you have a competent manager available. If your employees are caught stealing, this can spell the end of your business. Interview them thoroughly for their trustworthiness, not simply for their cleaning skills. This is especially important in high tech or knowledge-based firms, since industrial espionage and hacking often takes place by planting a competitor's or a malicious employee as a temporary cleaning worker. Businesses know this, and if they ask you should be able to assure your customers that you understand and have mitigated that risk.

Follow up with clients. Especially for cleaning crews that work at night, your first in-person contact with your customer may also be your last. Take the time to stop by, e-mail or call during regular business hours to solicit feedback on your crew's performance and ask if there are any other services or changes your customer would like.

Market continuously. Even when you are busy at work, as a business owner you should still spend time and money securing new customers and contracts in order to grow your business. Attend trade shows and vendor fairs, make cold calls or engage a service to do so for you, and send out mailings to businesses in your area. Offer specials to your current clients for referrals. You can even ask established clients for letters of recommendation and testimonials.